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Southern Ag Amine 2,4-D Weed Killer, 32 oz — selective broadleaf herbicide product photograph on a plain background
Southern Ag Amine 2,4-D Weed Killer, 32 oz — selective broadleaf herbicide (amine concentrate)

Selective Broadleaf Herbicide (amine concentrate)

Southern Ag Amine 2,4-D Weed Killer, 32 oz Review

★★★★☆ 4.4/5

our editor rating how we score

4.4/5 from 8,063 shoppers at Amazon — their number, not ours.

$18–$24

Typical price · 32 oz concentrate; rate per label by site

Affiliate links — see our disclosure. Commissions never influence verdicts.

Straight 2,4-D amine at concentrate prices — the base broadleaf active behind most three-way lawn products, without the other two.

Our Verdict

If you already know 2,4-D is what you need, buying it on its own is far cheaper than buying it inside a branded three-way, and this is the version with the largest body of user feedback on the platform at over eight thousand ratings. The amine salt is the formulation used on turf and pasture, as against the ester concentrates sold for brush in non-crop areas. Where it earns its place is breadth of site: 2,4-D is labelled across lawns, pasture and cereal-type situations, which makes it the one bottle an acreage owner is most likely to reach for repeatedly. Two limits worth stating plainly. It is a broadleaf herbicide, so it does nothing to grassy weeds and nothing to sedges — those need different chemistry entirely. And on the two weeds people most often buy it for, extension shortlists do not name it: neither Penn State nor MSU lists 2,4-D among the effective actives for clover, and creeping Charlie and wild violet answer to triclopyr instead. Read the target list rather than assuming a broadleaf product covers every broadleaf.

✅ Pros

  • 8,063 Amazon ratings — by far the largest evidence base of any herbicide on this site
  • Around $21 for 32 oz of concentrate, a fraction of the cost per treated area of a ready-to-spray
  • Amine salt, the formulation used on turf and pasture rather than the brush ester
  • Labelled across a wide range of sites, which suits a property with more than a lawn

⚠️ Cons

  • Broadleaf only — no effect on grassy weeds or sedges
  • Not on extension's shortlist for clover, creeping Charlie or wild violet, which are common reasons people buy it
  • Most 2,4-D products carry turf injury warnings above roughly 85–90°F
  • Concentrate needs a sprayer and correct dilution; a surfactant is required by some labels

Product type

Selective Broadleaf Herbicide (amine concentrate)

Active ingredient

2,4-D, dimethylamine salt

Price range

$18–$24

Coverage

32 oz concentrate; rate per label by site

Best for

Broadleaf weeds across lawn, pasture and acreage where you want the active on its own rather than inside a branded blend

our editor rating

4.4 out of 5

Where our facts come from

Label read on the registrant's own PDF

EPA Reg. No. 48273-4-829

Read the label yourself →

We read the printed label published by the company that holds the registration. EPA hosts no PDF for this one, so this is the best available text.

What we found when we read it

Label read 2026-08-02 (registrant's own PDF, EPA Est. No. 829-FL-1). 2,4-D dimethylamine salt, 46.8%, acid equivalent 38.4% = 3.8 lb/gal. Sites on the front panel: pastures and rangeland, lawns, golf courses, cemeteries, parks and similar ornamental turf, fences, ditchbanks, roadsides, industrial sites. A separate SMALL GRAINS section covers wheat, barley, oats and rye and is the basis of weed-control-in-cereal-food-plots: it opens 'Not underseeded with a Legume crop', gives 1 1/3 to 2 pints/acre for barley, wheat and rye but only 1/2 to 1 pint for OATS, times the application at 'full tiller stage (usually 4 to 8 inches tall)', and bars application before tillering or from early boot to milk stage. Season caps: one post-emergence application per crop cycle, max 2 1/2 pints/acre per application, 3 2/3 pints/acre per crop cycle. Grazing: do not graze or feed treated forage within 2 weeks; do not use treated straw for livestock feed.

Where this page and the container disagree, the container wins — the label is the legal authority on rates and restrictions. How to read one yourself.

Where This Product Matters

Matched against each state's actual disease, weed and pest pressure.

DandelionCommon chickweedBroadleaf and common plantainChickweed and other cool-wet-condition annuals in the Southeast

Application window: June through July, inside the same short window everything else happens in. There is no autumn second chance

Henbit

Application window: Bounded by the label's temperature ceiling rather than the calendar — spring treatments finish before the June heat arrives, and nothing selective goes down again until September cools off

Dandelion

Application window: May–June and September; high-altitude sun makes stressed turf easy to injure, so spot-treat rather than blanket-spray

DandelionBroadleaf plantain

Application window: Broadleaf sprays in May–June and again in September, when the weeds are moving sugars to the roots; skip July and August, when a stressed cool-season lawn takes the injury and the weed does not

Dandelion

Application window: Late April into June, then September into October; skip the July and early August heat, which is also when UI's own fertilizer schedule goes quiet

Dandelion

Application window: May–June and September; fall beats creeping charlie best

Dandelion

Application window: October is the most effective month for broadleaf weeds; never apply above 80°F or to drought-stressed turf

Dandelion

Application window: October, and October is most of it — but check the wind and the date against what is happening in the fields, because early-summer growth-regulator drift is a real seasonal risk here and your own spray carries the same way

Henbit and other winter annuals, which own an eastern Kansas lawn in MarchDandelion

Application window: April into May and again in September–October; avoid July and August, when a tall fescue lawn here is already at its limit

Henbit

Application window: April–May and September–October; autumn is the knockout window for the wild garlic that defines a Kentucky winter lawn

DandelionBroadleaf plantainCommon chickweed

Application window: June, then a narrow late-August to mid-September window. Maine's usable autumn is the shortest in New England

Dandelion

Application window: A narrow autumn is the real window here: late September into October, after the summer heat and before New England's early frost closes the season

Dandelion

Application window: May–June and September; autumn is the stronger window for perennial broadleaf weeds

Dandelion

Application window: Late May–June and September; autumn is the stronger window for perennial broadleaf weeds

HenbitDandelion

Application window: April–May and September–October; skip summer sprays on drought-stressed fescue

DandelionCommon plantainCanada thistle and other listed noxious weeds pushing in from unmanaged edges

Application window: June, then late August into September. In a sub-100-day valley there is no third chance

DandelionHenbit and other winter annuals

Application window: Late spring and again from late August through September, when perennial broadleaf weeds are moving reserves to the root

DandelionBroadleaf plantainCommon chickweed

Application window: Late May into June, then late August through September. The autumn window closes earlier here than anywhere else in southern New England

DandelionBroadleaf plantain

Application window: May and September–October; autumn is the knockout window for perennial broadleaf weeds

Kochia and Russian thistle at the dry margins

Application window: Spring and early autumn; in the south skip the June heat entirely, and in the north the usable autumn window closes by early October

Dandelion

Application window: May and September–October; autumn is the knockout window for perennial broadleaf weeds

Henbit

Application window: April–May and September–October; avoid spraying heat-stressed fescue in July–August

DandelionCommon plantain

Application window: Early to mid-June, then late August into early September. There is no third opportunity

DandelionBroadleaf plantain

Application window: May–June and September; fall applications hit dandelion taproots hardest

Henbit

Application window: Judged by wind before season: sustained wind is Oklahoma's normal condition, so the usable spray days are calm mornings in April, May and September rather than whole months

Dandelion

Application window: March–May and September–October; the long mild shoulder seasons give more usable spray days than most states get

Dandelion

Application window: May and September — fall is the knockout window for perennial broadleaf weeds

DandelionBroadleaf plantain

Application window: Broadleaf work in May–June and again in September; the September pass is the one that holds, because the weed is moving reserves down

DandelionCommon plantain

Application window: Early to mid-June, then late August into September, which is the pass that actually holds on perennial broadleaf weeds

Henbit

Application window: April–May and September–October; skip sprays on drought-stressed summer fescue

Henbit

Application window: April–early June and September–October; avoid herbicides above 90°F

Dandelion

Application window: May and September, avoiding the intense midsummer heat on the label

DandelionBroadleaf plantainCommon chickweed

Application window: Late May through June, then a short late-August to mid-September window. Vermont's autumn window is the narrowest in New England

Dandelion

Application window: April–May and September–October; skip sprays on heat-stressed fescue in July and August

Dandelion

Application window: April–May and September–October; WSU caps applications at 80°F, stricter than the 85–90°F ceilings used elsewhere

Broadleaf plantain

Application window: April into May and again in September–October. Skip July and August: this is transition-zone country and a heat-stressed tall fescue lawn absorbs the injury the weed does not

DandelionBroadleaf plantain

Application window: Early to mid-fall is the favourable window for dandelion and other perennial broadleaf weeds

DandelionCommon plantainCanada thistle and other listed noxious species moving in from unmanaged edges

Application window: June, then late August into September. UW's own framing is useful: a slow-release application covers a 90 to 100 day growing season, which is roughly the entire Wyoming season

Common questions

Common Questions

How much does Southern Ag Amine 2,4-D Weed Killer, 32 oz cost?

Southern Ag Amine 2,4-D Weed Killer, 32 oz typically runs $18–$24, covering 32 oz concentrate; rate per label by site.

What does Southern Ag Amine 2,4-D Weed Killer, 32 oz treat?

Southern Ag Amine 2,4-D Weed Killer, 32 oz targets dandelion, plantain, chickweed, henbit, thistle.

What is the active ingredient in Southern Ag Amine 2,4-D Weed Killer, 32 oz?

2,4-D, dimethylamine salt, registered under EPA Reg. No. 48273-4-829.

What is the biggest downside of Southern Ag Amine 2,4-D Weed Killer, 32 oz?

Broadleaf only — no effect on grassy weeds or sedges

Real feedback

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