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Hi-Yield 2,4-D Selective Weed Killer, 1 Gallon — selective broadleaf herbicide product photograph on a plain background
Hi-Yield 2,4-D Selective Weed Killer, 1 Gallon — selective broadleaf herbicide (amine concentrate, acreage volume)

Selective Broadleaf Herbicide (amine concentrate, acreage volume)

Hi-Yield 2,4-D Selective Weed Killer, 1 Gallon Review

★★★★☆ 4.3/5

our editor rating how we score

4.4/5 from 1,657 shoppers at Amazon — their number, not ours.

$34–$42

Typical price · 1 gallon concentrate — acreage-scale volume

Affiliate links — see our disclosure. Commissions never influence verdicts.

The same 2,4-D amine in a gallon rather than a quart, which is the size that makes sense once you are spraying a paddock rather than a lawn.

Our Verdict

This is a volume decision rather than a chemistry one. The active is 2,4-D amine, the same working ingredient as the quart bottles, and the listing describes it for acreage operators — which is the honest use case. On a suburban lawn a gallon of 2,4-D concentrate is more than you will use before you should be questioning why you are spraying that much; on two to twenty acres of pasture or paddock it is the size that stops you re-ordering mid-job. The per-application cost falls sharply at this volume. Everything true of 2,4-D generally applies here: broadleaf only, nothing on grassy weeds or sedges, a heat restriction on most labels, and a target list that is narrower than the phrase broadleaf herbicide suggests. For pasture specifically, the grazing and haying restriction on the label is the number to read before the rate — UGA notes restrictions across products range from seven days to a year, and that a product with no beef restriction may still carry one for dairy.

✅ Pros

  • Gallon volume drops the cost per treated acre well below quart-sized bottles
  • 1,657 Amazon ratings
  • Amine formulation, appropriate for grazed pasture rather than the brush ester
  • Labelled across the range of sites an acreage owner actually has

⚠️ Cons

  • Far more product than a suburban lawn needs, and herbicide does not improve in storage
  • Broadleaf only — no grassy weeds, no sedges
  • Grazing and haying restrictions apply on pasture and are product-specific; read them before the rate
  • Heat restrictions on most 2,4-D labels still apply at this volume

Product type

Selective Broadleaf Herbicide (amine concentrate, acreage volume)

Active ingredient

2,4-D dimethylamine salt 11.84% (9.83% acid equivalent, 0.85 lb per gallon)

Price range

$34–$42

Coverage

1 gallon concentrate — acreage-scale volume

Best for

Pasture, paddock and acreage broadleaf control, where a quart bottle runs out mid-job

our editor rating

4.3 out of 5

Where our facts come from

Label read on the registrant's own PDF

EPA Reg. No. 228-238-7401

Read the label yourself →

We read the printed label published by the company that holds the registration. EPA hosts no PDF for this one, so this is the best available text.

What we found when we read it

Label read 2026-08-02 on the registrant's own site. EPA Reg. 228-238-7401 — a distributor product: base registration 228-238 sold under Voluntary Purchasing Group's company number 7401, the same distributor code as the other Hi-Yield and Fertilome products here, so the printed label is a subset of the base label's uses. Dimethylamine salt of 2,4-D 11.84%, acid equivalent 9.83% = 0.85 lb per gallon. Note how low that acid equivalent is next to the agricultural esters we review at 5.5 lb/gal — the comparison that makes 'gallon volume' misleading on this shelf unless you compare acid equivalent rather than pack size.

Where this page and the container disagree, the container wins — the label is the legal authority on rates and restrictions. How to read one yourself.

Where This Product Matters

Matched against each state's actual disease, weed and pest pressure.

DandelionBroadleaf and common plantain

Application window: June through July, inside the same short window everything else happens in. There is no autumn second chance

Dandelion

Application window: May–June and September; high-altitude sun makes stressed turf easy to injure, so spot-treat rather than blanket-spray

DandelionBroadleaf plantain

Application window: Broadleaf sprays in May–June and again in September, when the weeds are moving sugars to the roots; skip July and August, when a stressed cool-season lawn takes the injury and the weed does not

Dandelion

Application window: Late April into June, then September into October; skip the July and early August heat, which is also when UI's own fertilizer schedule goes quiet

Dandelion

Application window: May–June and September; fall beats creeping charlie best

Dandelion

Application window: October is the most effective month for broadleaf weeds; never apply above 80°F or to drought-stressed turf

Dandelion

Application window: October, and October is most of it — but check the wind and the date against what is happening in the fields, because early-summer growth-regulator drift is a real seasonal risk here and your own spray carries the same way

Dandelion

Application window: April into May and again in September–October; avoid July and August, when a tall fescue lawn here is already at its limit

DandelionBroadleaf plantain

Application window: June, then a narrow late-August to mid-September window. Maine's usable autumn is the shortest in New England

Dandelion

Application window: A narrow autumn is the real window here: late September into October, after the summer heat and before New England's early frost closes the season

Dandelion

Application window: May–June and September; autumn is the stronger window for perennial broadleaf weeds

Dandelion

Application window: Late May–June and September; autumn is the stronger window for perennial broadleaf weeds

Dandelion

Application window: April–May and September–October; skip summer sprays on drought-stressed fescue

DandelionCommon plantainCanada thistle and other listed noxious weeds pushing in from unmanaged edges

Application window: June, then late August into September. In a sub-100-day valley there is no third chance

Dandelion

Application window: Late spring and again from late August through September, when perennial broadleaf weeds are moving reserves to the root

DandelionBroadleaf plantain

Application window: Late May into June, then late August through September. The autumn window closes earlier here than anywhere else in southern New England

DandelionBroadleaf plantain

Application window: May and September–October; autumn is the knockout window for perennial broadleaf weeds

Kochia and Russian thistle at the dry margins

Application window: Spring and early autumn; in the south skip the June heat entirely, and in the north the usable autumn window closes by early October

Dandelion

Application window: May and September–October; autumn is the knockout window for perennial broadleaf weeds

DandelionCommon plantain

Application window: Early to mid-June, then late August into early September. There is no third opportunity

DandelionBroadleaf plantain

Application window: May–June and September; fall applications hit dandelion taproots hardest

Creeping buttercup (wet valley ground)Dandelion

Application window: March–May and September–October; the long mild shoulder seasons give more usable spray days than most states get

Dandelion

Application window: May and September — fall is the knockout window for perennial broadleaf weeds

DandelionBroadleaf plantain

Application window: Broadleaf work in May–June and again in September; the September pass is the one that holds, because the weed is moving reserves down

DandelionCommon plantain

Application window: Early to mid-June, then late August into September, which is the pass that actually holds on perennial broadleaf weeds

Dandelion

Application window: May and September, avoiding the intense midsummer heat on the label

DandelionBroadleaf plantain

Application window: Late May through June, then a short late-August to mid-September window. Vermont's autumn window is the narrowest in New England

Dandelion

Application window: April–May and September–October; skip sprays on heat-stressed fescue in July and August

ButtercupDandelion

Application window: April–May and September–October; WSU caps applications at 80°F, stricter than the 85–90°F ceilings used elsewhere

Broadleaf plantain

Application window: April into May and again in September–October. Skip July and August: this is transition-zone country and a heat-stressed tall fescue lawn absorbs the injury the weed does not

DandelionBroadleaf plantain

Application window: Early to mid-fall is the favourable window for dandelion and other perennial broadleaf weeds

DandelionCommon plantainCanada thistle and other listed noxious species moving in from unmanaged edges

Application window: June, then late August into September. UW's own framing is useful: a slow-release application covers a 90 to 100 day growing season, which is roughly the entire Wyoming season

Common questions

Common Questions

How much does Hi-Yield 2,4-D Selective Weed Killer, 1 Gallon cost?

Hi-Yield 2,4-D Selective Weed Killer, 1 Gallon typically runs $34–$42, covering 1 gallon concentrate — acreage-scale volume.

What does Hi-Yield 2,4-D Selective Weed Killer, 1 Gallon treat?

Hi-Yield 2,4-D Selective Weed Killer, 1 Gallon targets thistle, buttercup, dandelion, plantain, ragweed.

What is the active ingredient in Hi-Yield 2,4-D Selective Weed Killer, 1 Gallon?

2,4-D dimethylamine salt 11.84% (9.83% acid equivalent, 0.85 lb per gallon), registered under EPA Reg. No. 228-238-7401.

What is the biggest downside of Hi-Yield 2,4-D Selective Weed Killer, 1 Gallon?

Far more product than a suburban lawn needs, and herbicide does not improve in storage

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