
Weed Control
Glyphosate vs Glufosinate: The Roots Are the Difference
Glufosinate is faster and matches glyphosate on annuals and nutsedge. NC State: it does not translocate throughout the plant — so perennials come back.

Non-Selective Contact Herbicide (glufosinate concentrate)
★★★★☆ 3.9/5
our editor rating how we score4.3/5 from 44 shoppers at Amazon — their number, not ours.
$35–$44
Typical price · 32 oz concentrate — the listing states it makes 16 gallons
Affiliate links — see our disclosure. Commissions never influence verdicts.
The main glyphosate alternative — but NC State is clear it does not translocate to roots, so perennials come back.
The honest use for glufosinate is as a fast, glyphosate-free burndown, and the honest limit comes from NC State: glufosinate moves within treated foliage but does not translocate throughout the plant, and does not translocate to the roots of treated plants. So it is faster-acting than glyphosate and visibly more dramatic, and it does not kill an established perennial — the crown and roots survive and regrow. That makes it a good choice for annual weeds, seedlings and hardscape where speed matters and permanence is not on offer anyway, and a poor choice for a bramble stand or a lawn you are killing before renovation. It is also useful where glyphosate resistance has developed, since the mode of action is different. NC State's other relevant point applies here too: none of these products have residual activity in soils, so nothing is prevented. 32 oz making 16 gallons is a sensible homeowner quantity, though 44 ratings is a thin evidence base compared with the glyphosate options beside it.
Product type
Non-Selective Contact Herbicide (glufosinate concentrate)
Active ingredient
Glufosinate-ammonium 24.5%
Price range
$35–$44
Coverage
32 oz concentrate — the listing states it makes 16 gallons
Best for
A fast glyphosate-free burndown of annual weeds and seedlings, where regrowth from perennial roots is acceptable
our editor rating
3.9 out of 5
Label read on the registrant's own PDF
EPA Reg. No. 42750-365-72838
We read the printed label published by the company that holds the registration. EPA hosts no PDF for this one, so this is the best available text.
Label read 2026-08-05 from Sanco Industries' own published PDF, which closes a dead end this record had documented as unresolved. EPA Reg. No. 42750-365-72838 — three parts, so it is a distributor version of Albaugh's 42750-365, and it carries the same distributor number (72838) as the Liquid Harvest three-way in this catalogue. Glufosinate-ammonium 24.5%, CAS 77182-82-2, equivalent to 2.34 lb ai per gallon. Signal word CAUTION, not a restricted-use pesticide. Rainfast 4 hours. The restriction that matters most is geographic and it is printed on the label: 'In the State of New York Only: Not For Use in Nassau and Suffolk Counties.' Turf use is far narrower than the product's non-selective reputation suggests — the only turf site on the label is well-established ornamental DORMANT hybrid or common bermudagrass, applied before spring green-up, at 48–80 fl oz per acre, with the label warning of severe turfgrass injury or delayed green-up otherwise. Caps: 80 fl oz (1.5 lb ai) per acre per year, and no more than 3 broadcast applications per year at reduced rates.
Where this page and the container disagree, the container wins — the label is the legal authority on rates and restrictions. How to read one yourself.
Matched against each state's actual disease, weed and pest pressure.
Application window: May and September–October; autumn is the knockout window for perennial broadleaf weeds
⚖️ The label carries a county-level prohibition for this state: not for use in Nassau or Suffolk Counties. If you are on Long Island, this product is off-limits regardless of the site.
Common questions
Liquid Harvest 24.5% Glufosinate Herbicide, 32 oz typically runs $35–$44, covering 32 oz concentrate — the listing states it makes 16 gallons.
Liquid Harvest 24.5% Glufosinate Herbicide, 32 oz targets annual weeds, seedlings, hardscape weeds.
Glufosinate-ammonium 24.5%, registered under EPA Reg. No. 42750-365-72838.
NC State: does not translocate to roots, so perennials regrow from the crown
Real feedback
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Weed Control
Glufosinate is faster and matches glyphosate on annuals and nutsedge. NC State: it does not translocate throughout the plant — so perennials come back.

Lawn Care Guides
Penn State decides this with two measurements, not a feeling: how much of the lawn is desirable grass, and how deep the thatch is. Under 50% is the kill-off line.

Weed Control
Every ready-to-use bottle for hardscape is a contact killer. NC State: they knock down top growth only, and none have residual activity in soil.
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